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Takara
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T210
|
Anti-CD3 mAb GMP grade
|
1.0 mg/1.0 ml
|
2,515,000¿ø
|
|
|
Product index
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Overview
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T cell therapy ¿¬±¸
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Gene editing
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TCR/BCR Profiling
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¡ØAnti-CD3 mAb GMP grade (Code T210) Á¦Ç° ÁÖ¹®½Ã Àü¿ë ÁÖ¹®¼¸¦ ÀÛ¼ºÇÏ¿© ´ÙÄ«¶óÄÚ¸®¾Æ([email protected])·Î º¸³»ÁÖ¼¼¿ä.
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º» Á¦Ç°Àº GMP gradeÀÇ Anti-CD3 monoclonal antibody·Î¼ T cellÀÇ Áõ½Ä ÀÚ±ØÇÏ¿©, È®´ë¹è¾ç½Ã (expansion) »ç¿ëµÈ´Ù. Anti-CD3 mAb GMP grade´Â
°¡Àå ÀϹÝÀûÀ¸·Î T cell È®´ë¹è¾ç¿¡ »ç¿ëµÇ´Â ¡®OKT3¡¯ Clone (mouse IgG2a)À¸·Î Á¦À۵ǾúÀ¸¸ç, º» Á¦Ç°°ú RetroNectin¢ç (Code T100A)À» ÇÔ²² »ç¿ëÇϸé,
T cellÀ» °¡Àå È¿À²ÀûÀ¸·Î È®´ë¹è¾ç ÇÒ ¼ö ÀÖ´Ù.
GMP grade·Î Á¦Á¶ ¹× Ç°Áú °ü¸®µÈ Á¦Ç°À¸·Î, ex-vivo¿¡¼ÀÇ À¯ÀüÀÚ Ä¡·á¿Í ¼¼Æ÷ Á¦ÀÛ µîÀÇ Àӻ󿬱¸¿¡ »ç¿ë °¡´ÉÇÏ´Ù.
(A) È®´ë¹è¾ç·ü
(B) CD3/CD4/CD8 ºñÀ²
(C) ¼¼Æ÷ µ¶¼º È°¼º ÃøÁ¤
±×¸² 1. T cellÀÇ È®´ë¹è¾ç¿¡¼ OKT3ÀÇ ¼º´É ºñ±³. Peripheral blood mononuclear cell (PBMC)À» Anti-CD3 mAbÀÇ ÀÚ±ØÇÏ¿¡¼ 5ÀÏ°£ ¹è¾ç ÈÄ,
T cell ¹è¾ç ¹èÁö¿¡ ÀûÀýÈ÷ Èñ¼®Çϸé¼
9ÀÏ°£ Ãß°¡ ¹è¾çÇÏ¿´´Ù. È®´ë¹è¾ç ÈÄ (A) ¼¼Æ÷ Áõ½Ä·ü, (B) Ç¥ÇöÇü (CD3/CD4/CD8 ºñÀ²), (C) K562¼¼Æ÷ÀÇ ¼¼Æ÷ µ¶¼º È°¼ºÀ»
ºñ±³ÇÑ °á°ú, Anti-CD3 GMP grade´Â Ÿ»ç Á¦Ç°°ú µ¿µîÇÑ ¼º´ÉÀ» ³ªÅ¸³»¾ú´Ù.
º¸Á¸
-70¡É ÀÌÇÏ¿¡¼ º¸°ü
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Mouse Hybridoma cells
¼øµµ
>95% by HPLC
Æ÷Àå ÇüÅÂ
1.0 §· protein / 1.0 §¢ÀÇ ¿ë¾× Á¦Ç°À» 2 §¢ cryovial¿¡ Æ÷Àå
Application
- CIK (cytokine-induced killer)ÀÇ È®´ë¹è¾ç (Cytokine°ú ÇÔ²² »ç¿ë)
- T lymphocyteÀÇ È®´ë¹è¾ç (RetroNectin¢ç°ú ÇÔ²² »ç¿ë)
T cell È®´ë¹è¾ç °ü·ÃÁ¦Ç°
Keyword : OKT3,okt3,car-t,CAR-T,Tcell,t cell,t-cell